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Understanding Antibody Diversity in Immunology
Be introduced to the properties of human immunoglobulin isotypes antigen recognition by T-cell receptors. You will learn how the IgM and IgD immunoglobulins are derived from the same pre-mRNA transcript and expressed on the surface of mature B-cells. This complex material is arranged systematically and presented clearly so you will easily be able to understand the given concepts.Next it will explain the process of isotype switching and the different types of variation between immunoglobulins. The course then demonstrates the role of peptides binding and stabilizing the MHC molecule on the cell surface and the creation of new alleles by copying sequences from one MHC gene to another. It emphasizes the direct binding of the superantigens to the T-cell receptors and MHC molecules.Finally you will learn about the process of generating peptides from the ubiquitinated proteins. The cessation of antigen processing in dendritic cells through the reduced expression of the MARCH-1 E3 ligase is also discussed. ‘Understanding Antibody Diversity in Immunology’ is an informative course that will interest students studying life sciences genetic engineering and biotechnology.
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Disclaimer: Some of the links on this website are affiliate links, meaning we may earn a commission if you click through and make a purchase. This comes at no additional cost to you.
By clicking the button above, you acknowledge that you will be redirected to a third-party website and agree to their terms and conditions.
Product information, including title, description, and images, is sourced/provided by our affiliate partner, Alison US CA.
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Refer a friend and earn 0.05 CEC when they click the link, plus an additional 1.00 CEC if they register. Share this Product and boost your earnings together!